1700002935
自由基老化理论
1700002936
1700002937
Barja G. Updating the mitochondrial free-radical theory of aging: an integrated view, key aspects, and confounding concepts. Antioxidants and Redox Signalling19: 1420–45 (2013).
1700002938
1700002939
Gerschman R, Gilbert DL, Nye SW, Dwyer P, Fenn WO. Oxygen poisoning and X irradiation: a mechanism in common. Science119: 623–26 (1954).
1700002940
1700002941
Harmann D. Aging – a theory based on free-radical and radiation chemistry. Journal of Gerontology11: 298–300 (1956).
1700002942
1700002943
Murphy MP. How mitochondria produce reactive oxygen species. Biochemical Journal417: 1–13 (2009).
1700002944
1700002945
自由基老化理论的问题
1700002946
1700002947
Bjelakovic G, Nikolova D, Gluud LL, Simonetti RG, Gluud C. Antioxidant supplements for prevention of mortality in healthy participants and patients with various diseases. Cochrane Database of Systematic Reviewsdoi: 10.1002/14651858.CD007176 (2008).
1700002948
1700002949
Gutteridge JMC, Halliwell B. Antioxidants: Molecules, medicines, and myths. Biochemical Biophysical Research Communications393: 561–64 (2010).
1700002950
1700002951
Gnaiger E, Mendez G, Hand SC. High phosphorylation efficiency and depression of uncoupled respiration in mitochondria under hypoxia. Proceedings National Academy Sciences97: 11080–85 (2000)
1700002952
1700002953
Moyer MW. The myth of antioxidants. Scientific American308: 62–67 (2013).
1700002954
1700002955
自由基信号与衰老的关系
1700002956
1700002957
Lane N. Mitonuclear match: optimizing fitness and fertility over generations drives ageing within generations. BioEssays33: 860–69 (2011).
1700002958
1700002959
Moreno-Loshuertos R, Acin-Perez R, Fernandez-Silva P, Movilla N, Perez-Martos A, de Cordoba SR, Gallardo ME, Enriquez JA. Differences in reactive oxygen species production explain the phenotypes associated with common mouse mitochondrial DNA variants. Nature Genetics38: 1261–68 (2006).
1700002960
1700002961
Sobek S, Rosa ID, Pommier Y, et al. Negative regulation of mitochondrial transcrioption by mitochondrial topoisomerase I. Nucleic Acids Research41: 9848–57 (2013).
1700002962
1700002963
自由基与生命率理论的关系
1700002964
1700002965
Barja G. Mitochondrial oxygen consumption and reactive oxygen species production are independently modulated: implications for aging studies. Rejuvenation Research10: 215–24 (2007).
1700002966
1700002967
Boveris A, Chance B. Mitochondrial generation of hydrogen peroxide – general properties and effect of hyperbaric oxygen. Biochemical Journal134: 707–16 (1973).
1700002968
1700002969
Pearl R. The Rate of Living. Being an Account of some Experimental Studies on the Biology of Life Duration. University of London Press, London (1928).
1700002970
1700002971
自由基与老年病
1700002972
1700002973
Desler C, Marcker ML, Singh KK, Rasmussen LJ. The importance of mitochondrial DNA in aging and cancer. Journal of Aging Research2011: 407536 (2011).
1700002974
1700002975
Halliwell B, Gutteridge JMC. Free Radicals in Biology and Medicine. 4th edition. Oxford University Press, Oxford (2007).
1700002976
1700002977
He Y, Wu J, Dressman DC, et al. Heteroplasmic mitochondrial DNA mutations in normal and tumour cells. Nature464: 610–14 (2010).
1700002978
1700002979
Lagouge M, Larsson N-G. The role of mitochondrial DNA mutations and free radicals in disease and ageing. Journal of Internal Medicine273: 529–43 (2013).
1700002980
1700002981
Lane N. A unifying view of aging and disease: the double agent theory. Journal of Theoretical Biology225: 531–40 (2003).
1700002982
1700002983
Moncada S, Higgs AE, Colombo SL. Fulfilling the metabolic requirements for cell proliferation. Biochemical Journal446: 1–7 (2012).
1700002984
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