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后记 来自深海
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真核生物还是原核生物？
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复杂生命的起源 图片来源
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图1: A tree of life showing the chimeric origin of complex cells. Reproduced with permission from: Martin W. Mosaic bacterial chromosomes: a challenge en route to a tree of genomes. BioEssays21: 99–104 (1999).
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图2: A timeline of life.
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图3: The complexity of eukaryotes. Reproduced with permission from: (A) Fawcett D. The Cell. WB Saunders, Philadelphia (1981). (B) courtesy of Mark Farmer, University of Georgia. (C) courtesy of Newcastle University Biomedicine Scientific Facilities; (D) courtesy of Peter Letcher, University of Alabama.
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图4: The Archezoa – the fabled (but false) missing link. Reproduced with permission from: (A) Katz LA. Changing perspectives on the origin of eukaryotes. Trends in Ecology and Evolution13: 493–497 (1998). (B) Adam RD, Biology of Giardia lamblia. Clinical Reviews in Microbiology14: 447–75 (2001).
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图5: The ‘supergroups’ of eukaryotes. Reproduced with permission from: Koonin EV. The incredible expanding ancestor of eukaryotes. Cell 140: 606–608 (2010).
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图6: The black hole at the heart of biology. Photomicrograph reproduced with permission from: Soh EY, Shin HJ, Im K. The protective effects of monoclonal antibodies in mice from Naegleria fowleri infection. Korean Journal of Parasitology. 30: 113–123 (1992).
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图7: Structure of a lipid membrane. Reproduced with permission from: Singer SJ, Nicolson GL. The fluid mosaic model of the structure of cell membranes. Science 175: 720–31 (1972).
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图8: Complex I of the respiratory chain. Reproduced with permissions from: (A) Sazanov LA, Hinchliffe P. Structure of the hydrophilic domain of respiratory complex I from Thermus thermophiles. Science 311: 1430–1436 (2006). (B) Baradaran R, Berrisford JM, Minhas GS, Sazanov LA. Crystal structure of the entire respiratory complex I. Nature 494: 443–48 (2013). (C). Vinothkumar KR, Zhu J, Hirst J. Architecture of mammalian respiratory complex I. Nature 515: 80–84 (2014).
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图9: How mitochondria work. Photomicrograph reproduced with permission from: Fawcett D. The Cell. WB Saunders, Philadelphia (1981).
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图10: Structure of the ATP synthase. Reproduced with permission from: David S Goodsell. The Machinery of Life. Springer, New York (2009).
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图11: Iron-sulphur minerals and iron-sulphur clusters. Modified with permission from: Russell MJ, Martin W. The rocky roots of the acetyl CoA pathway. Trends in Biochemical Sciences29: 358063 (2004).
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图12: Deep-sea hydrothermal vents. Photographs reproduced with permission from Deborah S Kelley and the Oceanography Society; from Oceanography18 September 2005.
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图13: Extreme concentration of organics by thermophoresis. Reproduced with permission from: (a-c) Baaske P, Weinert FM, Duhr S, et al. Extreme accumulation of nucleotides in simulated hydrothermal pore systems. Proceedings National Academy Sciences USA104: 9346–9351 (2007). (d) Herschy B, Whicher A, Camprubi E, Watson C, Dartnell L, Ward J, Evans JRG, Lane N. An origin-of-life reactor to simulate alkaline hydrothermal vents. Journal of Molecular Evolution79: 213–27 (2014).
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图14: How to make organics from H2 and CO2. Reproduced with permission from: Herschy B, Whicher A, Camprubi E, Watson C, Dartnell L, Ward J, Evans JRG, Lane N. An origin-of-life reactor to simulate alkaline hydrothermal vents. Journal of Molecular Evolution79: 213–27 (2014).
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