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[9] S chweitzer, J. K. and Livingston, D. M. (1997). Destabilisation of CAG trinucleotide repeat tracts by mismatch repair mutations in yeast.Human Molecular Genetics 6: 349-55.
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[10] M angiarini, L. (1997). Instability of highly expanded CAG repeats in mice transgenic for the Huntington’s disease mutation. Nature Genetics 15: 197-200; Bates, G. P., Mangiarini, L., Mahal, A. and Davies, S. W. (1997). Transgenic models of Huntington’s disease.Human Molecular Genetics 6: 1633-7.
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[11] C hong, S. S. et al. (1997). Contribution of DNA sequence and CAG size to mutation frequencies of intermediate alleles for Huntington’s disease: evidence from single sperm analyses. Human Molecular Genetics 6: 301-10.
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[12] Wexler, N. S. (1992). The Tiresias complex: Huntington’s disease as a paradigm of testing for late-onset disorders. FASEB Journal 6: 2820-25.
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[13] Wexler, A. (1995). Mapping fate. University of California Press, Los Angeles.
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5号染色体
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在搜寻基因方面,最好的一本书是威廉·库克森的《基因猎人:基因组丛林中的冒险》(奥鲁姆出版社,1994)。库克森的这本书是我搜寻哮喘基因的主要信息来源之一。
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[1] H amilton, G. (1998). Let them eat dirt. New Scientist, 18 July 1998: 26-31; Rook, G. A. W. and Stanford, J. L. (1998). Give us this day our daily germs. Immunology Today 19: 113-16.
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[2] C ookson, W. (1994). The gene hunters: adventures in the genome jungle.Aurum Press, London.
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[3] M arsh, D. G. et al. (1994). Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin-E concentrations.Science 264: 1152-6.
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[4] M artinez, F. D. et al. (1997). Association between genetic polymorphism of the beta-2-adrenoceptor and response to albuterol in children with or without a history of wheezing. Journal of Clinical Investigation 100
:3184-8.
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6号染色体
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罗莎琳德·阿登(Rosalind Arden)在即将出版的书中将讲述罗伯特·普洛明寻找影响智商的基因的故事。普洛明关于行为遗传学的教科书《行为遗传学》(第三版,1997),可读性强,堪称该领域的入门必备书。斯蒂芬·杰伊·古尔德的《人类的误测》(诺顿出版社,1981)很好地讲述了优生学和智商的早期历史。而劳伦斯·赖特(Lawrence Wright)的《双胞胎:基因、环境和身份的奥秘》(魏登菲尔德·尼科尔森出版社,1997)一书,读后令人颇有畅快之感。
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[1] C horney, M. J., Chorney, K., Seese, N., Owen, M. J., Daniels, J.,McGuffin, P., Thompson, L. A., Detterman, D. K., Benbow, C, Lubinski,D., Eley, T. and Plomin, R. (1998). A quantitative trait locus associated with cognitive ability in children. Psychological Science 9: 1-8.
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[2] Galton, F. (1883). Inquiries into human faculty. Macmillan, London.
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[3] Goddard, H. H. (1920), quoted in Gould, S. J. (1981). The mismeasure of man. Norton, New York.
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[4] N eisser, U. et al. (1996). Intelligence: knowns and unknowns. American Psychologist 51: 77-101.
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[5] P hilpott, M. (1996). Genetic determinism. In Tarn, H. (ed.), Punishment,excuses and moral development. Avebury, Aldershot.
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[6] W right, L. (1997). Twins: genes, environment and the mystery of identity.Weidenfeld and Nicolson, London.
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[7] S carr, S. (1992). Developmental theories for the 1990s: development and individual differences. Child Development 63: 1-19.
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[8] D aniels, M., Devlin, B. and Roeder, K. (1997). Of genes and IQ. In Devlin,B., Fienberg, S. E., Resnick, D. P. and Roeder, K. (eds), Intelligence,genes and success. Copernicus, New York.
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[9] H errnstein, R. J. and Murray, C. (1994). The bell curve. The Free Press,New York.
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[10] H aier, R. et al. (1992). Intelligence and changes in regional cerebral glucose metabolic rate following learning. Intelligence 16: 415-26.
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[11] Gould, S. J. (1981). The mismeasure of man. Norton, New York.
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[12] Furlow, F. B., Armijo-Prewitt, T., Gangestad, S. W. and Thornhill,R. (1997). Fluctuating asymmetry and psychometric intelligence.Proceedings of the Royal Society of London, Series B 264: 823-9.
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