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I 关于天花病毒的起源，参见：Hughes, A. L.; Irausquin, S.; Friedman, R.(2010). The evolutionary biology of pox viruses.Infection, genetics and evolution, 10 (1): 50–59。
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II 关于最复杂的拟菌病毒基因组，参见：Abrahão, J.; Silva, L.; Silva, L. S.; et al.(2018). Tailed giant Tupanvirus possesses the most complete translational apparatus of the known virosphere.Nature communications, 9(749)。
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III Judd, B. H. (2001). Nucleic acids as genetic material. In eLS, (Ed.). https://doi.org/10.1038/npg.els.0000807.
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IV 库宁的论文，参见：Koonin, E.; Senkevich, T.; Dolja, V.(2006). The ancient Virus World and evolution of cells.Biologydirect, 1(29)。
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第十二章
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I 关于甲醛聚糖反应产生生物活性的多种单糖，以及它对RNA世界假说的意义，参见：Cleaves H. J.(2011). Formosereaction. In: Gargaud M. et al.(eds).Encyclopedia of Astrobiology. Berlin, Heidelberg: Springer; Harrison, S.; Lane, N.(2018).Life as a guide to prebiotic nucleotide synthesis.Nature communications, 9(5176).
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II Furukawa, Yoshihiro; Chikaraishi, Yoshito; Ohkouchi, Naohiko; et al. (2019). Extraterrestrial ribose and other sugars in prim itive meteorites.Proceedings of the National Academy of Sciences, 116(49): 24440–24445.
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III Powner, M. W.; Gerland, B.; Sutherland, J. D.(2009). Synthesis of activated pyrimidine ribonucleotides in prebiotically plausible conditions.Nature, 459(7244): 239–242.
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IV Martin. W.; Russell. M. J.(2006). On the origin of biochemistry at an alkaline hydrothermal vent.Philosophical transactions of The Royal Society B Biological Sciences, 362(1486): 1887–1925；Harrison, S.; Lane, N.; Life as a guide to prebiotic nucleotide synthesis.Nature communications, 9(5176).
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V Herschy, B.; Whicher, A.; Camprubi, E.; et al.(2014). An origin-of-life reactor to simulate alkaline hydrothermal vents.Journal of molecular evolution, 79(5-6)
:213–227.
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VI Baaske, P.; Weinert, F. M.; Duhr, S.; et al.( 2007). Extreme accumulation of nucleotides in simulated hydrothermal pore systems.Proceedings of the National Academy of Sciences, 104(22): 9346-9351; Mast, C. B.; Schink, S.; Gerland, U.; Braun, D.( 2013). Escalation of polymerization in a thermal gradient.Proceedings of the National Academy of Sciences, 110(20)
:8030-8035.
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VII White, H. B. 3rd.(1976). Coenzymes as fossils of an earlier metabolic state.Journal of molecular evolution, 7(2)
:101-104; Penny, D.( 2005). An interpretative review of the origin of life research.Biology & Philosophy, 20
:633–671.
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VIII White, H. B. 3rd.(1976). Coenzymes as fossils of an earlier metabolic state.Journal of molecular evolution, 7(2)
:101-104; Graham, D. E.; White, R. H.(2002). Elucidation of methanogenic coenzyme biosyntheses: from spectroscopy to genomics.Natural product reports, 19(2)
:133-47.
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第十三章
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I 关于切赫发现内含子催化剪接，参见：Abelson, J.(2017). The discovery of catalytic RNA. Nature Reviews Molecular Cell Biology, 18: 653.
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II Nissen, P.; Hansen, J.; Ban, N.; et al.(2000).The structural basis of ribosome activity in peptide bond synthesis.Science, 289(5481): 920–929.
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III 关于最早提出RNA世界假说的三人的论文，参见：Woese, C. R.(1967).The genetic code: The molecular basisfor genetic expression. Harper & Row, 186; Crick, F. H.(1968). The origin of the genetic code.Journal of Molecular Biology, 38(3): 367–379; Orgel, L. E.(1968). Evolution of the genetic apparatus.Journal of Molecular Biology, 38(3): 381–393.
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IV 沃尔特·吉尔伯特提出RNA世界假说的论文，参见：Gilbert, W.(1986). Origin of life: The RNA world.Nature, 319(6055): 618–618.
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V 关于连接小段RNA的酶RNA，参见：Doudna, J. A.; Usman, N.; Szostak, J. W.(1993). Ribozyme-catalyzed primer ex tension by trinucleotides: A model for the RNA-catalyzed replication of RNA.Biochemistry, 32(8): 2111-2115.
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VI Wochner, A.; Attwater, J.; Coulson, A.; et al.(2011). Ribozyme-catalyzed transcription of an active ribozyme.Science, 332(6026)
:209-212.
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VII 关于24-3聚合酶，参见：Horning, D. P.; Joyce, G. F.(2016). Amplification of RNA by an RNA polymerase ribozyme.Proceedings of the National Academy of Sciences, 113(35): 9786-9791。
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VIII 关于酶RNA自复制组合，参见：Lincoln, T. A.; Joyce, G. F.(2009). Self-sustained replication of an RNA enzyme.Science.;323(5918)
:1229–1232.
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IX 关于自催化的酶RNA三元组合，参见：Vaidya, N.; Manapat, M. L.; Chen, I.A.; et al.(2012). Spontaneous network for mation among cooperative RNA replicators.Nature, 491: 72–77.
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第十四章
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I 关于斯皮格曼怪的发现，参见：Spiegelman, S.; Haruna, I.; Holland, I. B.;et al.(1965). The synthesis of a self-propagating and infectious nucleic acid with a purified enzyme.Proceedings of the National Academy of Sciences, 54(3)
:919–927。
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