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（季峰 赵静丽 黄怀德 宋震亚）
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内科学新进展 第二节 胃食管反流病研究的若干进展
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摘 要 由于生活习惯、饮食结构的变化，胃食管反流病（GERD）已成为较为常见的疾病，且其发生率日趋增高，GERD的诊治日益受到重视。近年研究进展，尤其是蒙特利尔GERD全球定义和分类、遗传因素和HP感染与GERD的关系、许多新的诊治技术的出现，使我们对该病的认识逐步深入，但仍有诸多问题有待进一步研究。
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Abstract For the changes of living condition and dietetical structure, gastroesophageal reflux disease（GERD）has become a common disease and its incidence is going up. The diagnosis and treatment of GERD have attracted considerable attention. It has been extensively studied and steady improvements have been made continuously, such as the Montreal definition and classification of GERD, the relationship between genetic factors and HP infection with GERD, and many new methods of diagnosis and treatment. Recognition of this disease gradually deepens, but many questions remain to be answered.
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胃食管反流病（gastroesophageal reflux disease, GERD）是一种困扰全球数百万人的常见疾病，且正在迅速成为临床中遇到的最重要的疾病——上胃肠道异常。肥胖、摄入过多脂肪、缺乏运动的生活方式等使GERD的患病率呈增长趋势。
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一、关于定义和分类
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目前认为关于GERD的定义是明确的，即GERD是指胃内容物反流入食管引起不适症状和（或）并发症的一种疾病。它的分类如下：
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（一）食管综合征
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（1）症状综合征：①典型反流综合征；②反流性胸痛综合征。
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