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XIV Hudson, R.; de Graaf, R.; Rodin, M. S.; et al.( 2020). CO2 reduction driven by a pH gradient.Proceedings of the NationalAcademy of Sciences, 117 (37): 22873-22879.
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XV 关于甲酰甲烷呋喃脱氢酶的催化原理：Wagner, T.; Ermler, U.; Shima, S.(2016). The methanogenic CO2 reduc ing-and-fixing enzyme is bifunctional and contains 46[4Fe-4S] clusters.Science, 354(6308): 114–117.
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XVI 关于甲酰甲烷呋喃脱氢酶，参见：Wagner, T.; Ermler, U.; Shima, S.(2016). The methanogenic CO2 reducing-and-fix ing enzyme is bifunctional and contains 46[4Fe-4S] clusters.Science, 354(6308): 114–117。
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XVII 关于钴咕啉铁硫蛋白的作用机理，参见：Svetlitchnaia, T.; Svetlitchnyi, V.; Meyer, O.; Dobbek, H.(2006). Struc tural insights into methyltransfer reactions of a corrinoid iron–sulfur protein involved in acetyl-CoA synthesis.Proceedingsof the National Academy of Sciences, 103(39): 14331-14336; Stich, T. A.; Seravalli, J.; Venkateshrao, S.; et al.(2006). Spec troscopic studies of the corrinoid/iron-sulfur protein from Moorella thermoacetica.Journal of the American Chemical Society, 128(15)
:5010–5020。
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XVIII 关于一氧化碳脱氢/乙酰辅酶A合成酶，参见：Dobbek, H.; Svetlitchnyi, V.; Gremer, L.; et al.(2001). Crystal struc ture of a carbon monoxide dehydrogenase reveals a [Ni-4Fe-5S] cluster.Science, 293(5533): 1281–1285; Lindahl, P. A.(2009).Nickel-carbon bonds in acetyl-coenzyme a synthases/carbon monoxide dehydrogenases.Metal ions in life sciences, 6
:133-150。
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XIX 关于乙酰辅酶A合成酶的铁硫簇A催化机制，参见：Hegg, E. L.(2004). Unraveling the Structure and mechanism of acetyl-coenzyme a synthase.Accounts of chemical research, 37(10): 775–783。
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第十章
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I 关于白烟囱假说对甲硫醇和硫代乙酸甲酯的倾向，参见：Martin, W.; Russell, M. J.( 2007). On the origin of biochemistry at an alkaline hydrothermal vent.Philosophical transactions of The Royal Society B Biological Sciences, 362(1486)
:1887–1925。
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II Kitadai, N.; Maruyama, S.(2018). Origins of building blocks of life: A review.Geoscience frontiers, 9(4): 1117-1153.
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III Camprubi, E.; Jordan, S. F.; Vasiliadou, R.; Lane, N.(2017). Iron catalysis at the origin of life.IUBMB Life, 69(6)
:373-381.
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IV Whicher, A.; Camprubi, E.; Pinna, S.; et al.(2018) Acetyl phosphate as a primordial energy currency at the origin of life.Origins of life and evolution of biospheres,;48(2)
:159–179.
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第四幕
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第十一章
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I 关于天花病毒的起源，参见：Hughes, A. L.; Irausquin, S.; Friedman, R.(2010). The evolutionary biology of pox viruses.Infection, genetics and evolution, 10 (1): 50–59。
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II 关于最复杂的拟菌病毒基因组，参见：Abrahão, J.; Silva, L.; Silva, L. S.; et al.(2018). Tailed giant Tupanvirus possesses the most complete translational apparatus of the known virosphere.Nature communications, 9(749)。
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III Judd, B. H. (2001). Nucleic acids as genetic material. In eLS, (Ed.). https://doi.org/10.1038/npg.els.0000807.
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IV 库宁的论文，参见：Koonin, E.; Senkevich, T.; Dolja, V.(2006). The ancient Virus World and evolution of cells.Biologydirect, 1(29)。
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第十二章
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I 关于甲醛聚糖反应产生生物活性的多种单糖，以及它对RNA世界假说的意义，参见：Cleaves H. J.(2011). Formosereaction. In: Gargaud M. et al.(eds).Encyclopedia of Astrobiology. Berlin, Heidelberg: Springer; Harrison, S.; Lane, N.(2018).Life as a guide to prebiotic nucleotide synthesis.Nature communications, 9(5176).
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II Furukawa, Yoshihiro; Chikaraishi, Yoshito; Ohkouchi, Naohiko; et al. (2019). Extraterrestrial ribose and other sugars in prim itive meteorites.Proceedings of the National Academy of Sciences, 116(49): 24440–24445.
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III Powner, M. W.; Gerland, B.; Sutherland, J. D.(2009). Synthesis of activated pyrimidine ribonucleotides in prebiotically plausible conditions.Nature, 459(7244): 239–242.
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IV Martin. W.; Russell. M. J.(2006). On the origin of biochemistry at an alkaline hydrothermal vent.Philosophical transactions of The Royal Society B Biological Sciences, 362(1486): 1887–1925；Harrison, S.; Lane, N.; Life as a guide to prebiotic nucleotide synthesis.Nature communications, 9(5176).
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V Herschy, B.; Whicher, A.; Camprubi, E.; et al.(2014). An origin-of-life reactor to simulate alkaline hydrothermal vents.Journal of molecular evolution, 79(5-6)
:213–227.
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VI Baaske, P.; Weinert, F. M.; Duhr, S.; et al.( 2007). Extreme accumulation of nucleotides in simulated hydrothermal pore systems.Proceedings of the National Academy of Sciences, 104(22): 9346-9351; Mast, C. B.; Schink, S.; Gerland, U.; Braun, D.( 2013). Escalation of polymerization in a thermal gradient.Proceedings of the National Academy of Sciences, 110(20)
:8030-8035.
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VII White, H. B. 3rd.(1976). Coenzymes as fossils of an earlier metabolic state.Journal of molecular evolution, 7(2)
:101-104; Penny, D.( 2005). An interpretative review of the origin of life research.Biology & Philosophy, 20
:633–671.
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